Three trees in Lilliesfield Avenue have been struck by a phenomenon so rare that the city's tree officers say they've never seen "anything like it before".
The branches on the trees have a strange cob-web like residue hanging off them akin to something from a horror film.
Even the trunks are covered in it, prompting bemused residents to go and take a look.
Richard Auckland, who lives nearby, said: "They are a spectacular, and somewhat creepy sight."
Tree maintenance workers from Gloucester City Council visited the street on Monday to investigate.
They are bird cherry trees, a native to Britain which produces a display of almond-scented white flowers every spring."
The cobwebs are caused by an invasion of bird cherry ermine moth caterpillars, which have created a vast nest.
The caterpillars feed on the trees, which are found across Europe, and they emerge as distinctive white moths with five rows of black dots. Experts say it is a natural phenomenon, and the council is planning to leave it alone.
Marcus Grodentz, spokesman for the city council, said: "The tree warden said he has never seen anything like it before.
"It doesn't pose a danger to people and, as far as we know, it doesn't pose a danger to the trees either.
"We know it has happened elsewhere in the country," Mr Grodentz said.
"They are keeping an eye on it, it is a very unusual sight."
The infestation was first spotted by volunteer tree wardens walking around Barnwood.